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AQP3 Antibody

CAT: 0223-60-438Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-438Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aquaporin 3 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0) . Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.
NCBI Gene ID
360
Swiss Prot
Q92482
Accession Number
Q92482
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This AQP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human AQP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AQP3
NCBI Official Name
Aquaporin-3
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Kim, N.H., et al. J. Invest. Dermatol. 130 (9) :2231-2239 (2010)
Background Reference 03
Ji, C., et al. Int. J. Mol. Med. 26 (2) :257-263 (2010)
Background Reference 04
Melis, M., et al. Dis. Colon Rectum 53 (6) :936-943 (2010)
Other Product Names
Aquaporin-3, AQP-3, Aquaglyceroporin-3, AQP3
Tested Applications
WB
Protein ID
2497938
Physical Properties
Liquid

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