SLCO1B3 Antibody

• Background:

  SLCO1B3 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]) .

• NCBI Gene ID:

  28234

• Swiss Prot:

  Q9NPD5

• Accession Number:

  Q9NPD5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SLCO1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-668 amino acids from the C-terminal region of human SLCO1B3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  77 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  SLCO1B3

• NCBI Official Name:

  Solute carrier organic anion transporter family member 1B3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)

• Background Reference 02:

  Weiner, M., et al. Antimicrob. Agents Chemother. 54 (10) :4192-4200 (2010)

• Background Reference 03:

  Kang, T.W., et al. Hum. Mol. Genet. 19 (18) :3672-3678 (2010)

• Background Reference 04:

  Takahashi, N., et al. J. Hum. Genet. (2010) In press :

• Other Product Names:

  Solute carrier organic anion transporter family member 1B3, Liver-specific organic anion transporter 2, LST-2, Organic anion transporter 8, Organic anion-transporting polypeptide 8, OATP-8, Solute carrier family 21 member 8, SLCO1B3, LST2, OATP1B3, OATP8, SLC21A8

• Tested Applications:

  WB

• Protein ID:

  27734563

• Physical Properties:

  Liquid