VSIG4 Antibody

• Background:

  This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

• NCBI Gene ID:

  11326

• Swiss Prot:

  Q9Y279

• Accession Number:

  Q9Y279

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This VSIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the C-terminal region of human VSIG4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  44 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  VSIG4

• NCBI Official Name:

  V-set and immunoglobulin domain-containing protein 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Guo, S., et al. Clin. Immunol. 136 (2) :282-291 (2010)

• Background Reference 02:

  Van Loo, P., et al. Haematologica 95 (3) :440-448 (2010)

• Background Reference 03:

  Xu, S., et al. Immunol. Lett. 128 (1) :46-50 (2010)

• Background Reference 04:

  He, J.Q., et al. Mol. Immunol. 45 (16) :4041-4047 (2008)

• Other Product Names:

  V-set and immunoglobulin domain-containing protein 4, Protein Z39Ig, VSIG4, CRIg, Z39IG

• Tested Applications:

  WB

• Protein ID:

  59799152

• Physical Properties:

  Liquid