VSIG4 Antibody

• Background :

  This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

• NCBI Gene ID :

  11326

• Swiss Prot :

  Q9Y279

• Accession Number :

  Q9Y279

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This VSIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the C-terminal region of human VSIG4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  44 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  VSIG4

• NCBI Official Name :

  V-set and immunoglobulin domain-containing protein 4

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Guo, S., et al. Clin. Immunol. 136 (2) :282-291 (2010)

• Background Reference 02 :

  Van Loo, P., et al. Haematologica 95 (3) :440-448 (2010)

• Background Reference 03 :

  Xu, S., et al. Immunol. Lett. 128 (1) :46-50 (2010)

• Background Reference 04 :

  He, J.Q., et al. Mol. Immunol. 45 (16) :4041-4047 (2008)

• Other Product Names :

  V-set and immunoglobulin domain-containing protein 4, Protein Z39Ig, VSIG4, CRIg, Z39IG

• Tested Applications :

  WB

• Protein ID :

  59799152

• Physical Properties :

  Liquid