CLEC6A Antibody

• Background:

  Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 [PubMed 15175046]) .

• NCBI Gene ID:

  93978

• Swiss Prot:

  Q6EIG7

• Accession Number:

  Q6EIG7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CLEC6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-163 amino acids from the C-terminal region of human CLEC6A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  24 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CLEC6A

• NCBI Official Name:

  C-type lectin domain family 6 member A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gavino, A.C., et al. Exp. Dermatol. 14 (4) :281-288 (2005)

• Background Reference 02:

  Flornes, L.M., et al. Immunogenetics 56 (7) :506-517 (2004)

• Background Reference 03:

  Kanazawa, N., et al. J. Invest. Dermatol. 122 (6) :1522-1524 (2004)

• Other Product Names:

  C-type lectin domain family 6 member A, C-type lectin superfamily member 10, Dendritic cell-associated C-type lectin 2, DC-associated C-type lectin 2, Dectin-2, CLEC6A, CLECSF10, DECTIN2

• Tested Applications:

  WB

• Protein ID:

  59797926

• Physical Properties:

  Liquid