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ARHGEF4 Antibody

CAT: 0223-60-045Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-045Size:400 µL
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Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.
NCBI Gene ID
10193024150649
Swiss Prot
Q9NR80
Accession Number
Q9NR80
Host
Rabbit
Reactivity
Human
Immunogen
This ARHGEF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-599 amino acids from the C-terminal region of human ARHGEF4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ARHGEF4
NCBI Official Name
Rho guanine nucleotide exchange factor 4
NCBI Organism
Homo sapiens
Background Reference 01
Lyons, R., et al. Leuk. Res. 34 (1) :109-115 (2010)
Background Reference 02
Kawasaki, Y., et al. J. Biol. Chem. 284 (33) :22436-22443 (2009)
Background Reference 03
Itoh, R.E., et al. J. Cell. Sci. 121 (PT 16), 2635-2642 (2008) :
Background Reference 04
Kurzik-Dumke, U., et al. Cell. Signal. 19 (9) :1973-1985 (2007)
Other Product Names
Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Asef, Asef1, ARHGEF4, KIAA1112
Tested Applications
WB
Protein ID
229463003
Physical Properties
Liquid

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