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FBXO44 Antibody

CAT: 0223-59-868Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-868Size:400 µL
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Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.
NCBI Gene ID
93611
Swiss Prot
Q9H4M3
Accession Number
Q9H4M3
Host
Rabbit
Reactivity
Human
Immunogen
This FBXO44 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-50 amino acids from the N-terminal region of human FBXO44.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FBXO44
NCBI Official Name
F-box only protein 44
NCBI Organism
Homo sapiens
Background Reference 01
Kumanomidou, T., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 66 (PT 1), 95-98 (2010) :
Background Reference 02
Glenn, K.A., et al. J. Biol. Chem. 283 (19) :12717-12729 (2008)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Jin, J., et al. Genes Dev. 18 (21) :2573-2580 (2004)
Other Product Names
F-box only protein 44, F-box protein FBX30, F-box/G-domain protein 3, FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A
Tested Applications
WB
Protein ID
61252661
Physical Properties
Liquid

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