FBXO44 Antibody

• Background:

  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.

• NCBI Gene ID:

  93611

• Swiss Prot:

  Q9H4M3

• Accession Number:

  Q9H4M3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FBXO44 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-50 amino acids from the N-terminal region of human FBXO44.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  30 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FBXO44

• NCBI Official Name:

  F-box only protein 44

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kumanomidou, T., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 66 (PT 1), 95-98 (2010) :

• Background Reference 02:

  Glenn, K.A., et al. J. Biol. Chem. 283 (19) :12717-12729 (2008)

• Background Reference 03:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 04:

  Jin, J., et al. Genes Dev. 18 (21) :2573-2580 (2004)

• Other Product Names:

  F-box only protein 44, F-box protein FBX30, F-box/G-domain protein 3, FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A

• Tested Applications:

  WB

• Protein ID:

  61252661

• Physical Properties:

  Liquid