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Sik1 Antibody

CAT: 0223-59-731Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-731Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
NCBI Gene ID
17691
Swiss Prot
Q60670
Accession Number
Q60670
Host
Rabbit
Reactivity
Human
Immunogen
This Sik1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-600 amino acids from the C-terminal region of mouse Sik1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
85 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Sik1
NCBI Official Name
Serine/threonine-protein kinase SIK1
NCBI Organism
Mus musculus
Background Reference 01
Romito, A., et al. PLoS ONE (2), E9029 (2010) :
Background Reference 02
Takemori, H., et al. Endocr. J. 56 (1) :121-130 (2009)
Background Reference 03
Berdeaux, R., et al. Nat. Med. 13 (5) :597-603 (2007)
Background Reference 04
Katoh, Y., et al. FEBS J. 273 (12) :2730-2748 (2006)
Other Product Names
Serine/threonine-protein kinase SIK1, HRT-20, Myocardial SNF1-like kinase, Salt-inducible kinase 1, SIK-1, Serine/threonine-protein kinase SNF1-like kinase 1, Serine/threonine-protein kinase SNF1LK, Sik1, Msk, Sik, Snf1lk
Tested Applications
WB
Physical Properties
Liquid

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