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CCR4 Antibody

CAT: 0223-59-665Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-665Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
NCBI Gene ID
1233
Swiss Prot
P51679
Accession Number
P51679
Host
Rabbit
Reactivity
Human
Immunogen
This CCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human CCR4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CCR4
NCBI Official Name
C-C chemokine receptor type 4
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)
Background Reference 03
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)
Background Reference 04
Klapa, S., et al. Clin. Exp. Rheumatol. 28 (1 SUPPL 57), 72-80 (2010) :
Other Product Names
C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4, K5-5, CD194, CCR4, CMKBR4
Tested Applications
WB
Protein ID
1705894
Physical Properties
Liquid

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