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CALCRL Antibody

CAT: 0223-59-491Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-491Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity) . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
NCBI Gene ID
10203
Swiss Prot
Q16602
Accession Number
Q16602
Host
Rabbit
Reactivity
Human
Immunogen
This CALCRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-367 amino acids from the Central region of human CALCRL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CALCRL
NCBI Official Name
Calcitonin gene-related peptide type 1 receptor
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Kuwasako, K., et al. Biochem. Biophys. Res. Commun. 392 (3) :380-385 (2010)
Background Reference 03
Chang, C.L., et al. J. Biol. Chem. 285 (2) :1075-1080 (2010)
Background Reference 04
Barwell, J., et al. Peptides 31 (1) :170-176 (2010)
Other Product Names
Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor, CALCRL, CGRPR
Tested Applications
WB
Protein ID
226693507
Physical Properties
Liquid

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