CALCA/CT Antibody

• Background:

  This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  796

• Swiss Prot:

  P01258

• Accession Number:

  P01258

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CALCA/CT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the C-terminal region of human CALCA/CT.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  15 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CALCA

• NCBI Official Name:

  Calcitonin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Giroux, S., et al. Bone 47 (5) :975-981 (2010)

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03:

  Lee, J.Y., et al. KoreanLab Med 30 (4) :406-413 (2010)

• Background Reference 04:

  Giovanella, L., et al. Clin. Chem. Lab. Med. 48 (8) :1163-1165 (2010)

• Other Product Names:

  Calcitonin, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, CCP, PDN-21, CALCA, CALC1

• Tested Applications:

  WB

• Protein ID:

  322510018

• Physical Properties:

  Liquid