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MTMR14 Antibody

CAT: 0223-59-225Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-225Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
NCBI Gene ID
64419
Swiss Prot
Q8NCE2
Accession Number
Q8NCE2
Host
Rabbit
Reactivity
Human
Immunogen
This MTMR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human MTMR14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MTMR14
NCBI Official Name
Myotubularin-related protein 14
NCBI Organism
Homo sapiens
Background Reference 01
Gibbs, E.M., et al. Autophagy 6 (6) :819-820 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Vergne, I., et al. EMBO J. 28 (15) :2244-2258 (2009)
Background Reference 04
Tosch, V., et al. Hum. Mol. Genet. 15 (21) :3098-3106 (2006)
Other Product Names
Myotubularin-related protein 14, 313-, HCV NS5A-transactivated protein 4 splice variant A-binding protein 1, NS5ATP4ABP1, hJumpy, MTMR14, C3orf29
Tested Applications
WB
Protein ID
118568016
Physical Properties
Liquid

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