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Mouse Tlk1 Antibody

CAT: 0223-59-114Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-114Size:400 µL
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Background
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly (By similarity) . Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10' (By similarity) .
NCBI Gene ID
228012
Swiss Prot
Q8C0V0
Accession Number
Q8C0V0
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Tlk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of mouse Tlk1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Human
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
87 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Tlk1
NCBI Official Name
Serine/threonine-protein kinase tousled-like 1
NCBI Organism
Mus musculus
Background Reference 01
Canfield, C., et al. BMC Mol. Biol. 10, 110 (2009) :
Background Reference 02
Taniwaki, T., et al. Dev. Growth Differ. 47 (3) :163-172 (2005)
Background Reference 03
Sunavala-Dossabhoy, G., et al. BMC Mol. Biol. 6, 19 (2005) :
Background Reference 04
Cobellis, G., et al. Nucleic Acids Res. 33 (4), E44 (2005) :
Other Product Names
Serine/threonine-protein kinase tousled-like 1, Tousled-like kinase 1, Tlk1
Tested Applications
WB
Physical Properties
Liquid

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