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DDX21 Antibody

CAT: 0223-59-054Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-054Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
NCBI Gene ID
9188
Swiss Prot
Q9NR30
Accession Number
Q9NR30
Host
Rabbit
Reactivity
Human
Immunogen
This DDX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-156 amino acids from the N-terminal region of human DDX21.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
87 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
DDX21
NCBI Official Name
Nucleolar RNA helicase 2
NCBI Organism
Homo sapiens
Background Reference 01
Holmstrom, T.H., et al. J. Biol. Chem. 283 (11) :7046-7053 (2008)
Background Reference 02
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Background Reference 03
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
Nucleolar RNA helicase 2, DEAD box protein 21, Gu-alpha, Nucleolar RNA helicase Gu, Nucleolar RNA helicase II, RH II/Gu, DDX21
Tested Applications
WB
Protein ID
76803555
Physical Properties
Liquid

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