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USP1 Antibody

CAT: 0223-58-780Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-780Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.
NCBI Gene ID
7398
Swiss Prot
O94782
Accession Number
O94782
Host
Rabbit
Reactivity
Human
Immunogen
This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 662-690 amino acids from the C-terminal region of human USP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
USP1
NCBI Official Name
Ubiquitin carboxyl-terminal hydrolase 1
NCBI Organism
Homo sapiens
Background Reference 01
Barroso, E., et al. Breast Cancer Res. Treat. 118 (3) :655-660 (2009)
Background Reference 02
McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18 (9) :2549-2552 (2009)
Background Reference 03
Cohn, M.A., et al. J. Biol. Chem. 284 (8) :5343-5351 (2009)
Background Reference 04
Cohn, M.A., et al. Mol. Cell 28 (5) :786-797 (2007)
Other Product Names
Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1
Tested Applications
WB
Physical Properties
Liquid

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