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PER1 Antibody

CAT: 0223-58-728Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-728Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
NCBI Gene ID
5187
Swiss Prot
O15534
Accession Number
O15534
Host
Rabbit
Reactivity
Human
Immunogen
This PER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1156-1183 amino acids from the C-terminal region of human PER1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
136 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PER1
NCBI Official Name
Period circadian protein homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Xia, H.C., et al. CanNeurol Sci 37 (3) :365-370 (2010)
Background Reference 02
Soria, V., et al. Neuropsychopharmacology 35 (6) :1279-1289 (2010)
Background Reference 03
Utge, S.J., et al. PLoS ONE (2), E9259 (2010) :
Background Reference 04
Zhu, Y., et al. Cancer Res. 69 (24) :9315-9322 (2009)
Other Product Names
Period circadian protein homolog 1, hPER1, Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui, PER1, KIAA0482, PER, RIGUI
Tested Applications
WB
Physical Properties
Liquid

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