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ARHGEF6 Antibody

CAT: 0223-58-685Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-685Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq].
NCBI Gene ID
9459
Swiss Prot
Q15052
Accession Number
Q15052
Host
Rabbit
Reactivity
Human
Immunogen
This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
87 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ARHGEF6
NCBI Official Name
Rho guanine nucleotide exchange factor 6
NCBI Organism
Homo sapiens
Background Reference 01
Maiti, A.K. Pharmacogenomics J. 10 (2) :94-104 (2010)
Background Reference 02
Eriguchi, M., et al. J. Neurol. Sci. 290 (1-2), 80-85 (2010) :
Background Reference 03
Takefuji, M., et al. J. Hum. Genet. 55 (1) :42-49 (2010)
Background Reference 04
Lim, J.W., et al. Scand. J. Gastroenterol. 44 (10) :1166-1172 (2009)
Other Product Names
Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6, ARHGEF6, COOL2, KIAA0006, PIXA
Tested Applications
WB
Protein ID
17371603
Physical Properties
Liquid

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