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ACSL3 Antibody

CAT: 0223-58-620Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-620Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
2181
Swiss Prot
O95573
Accession Number
O95573
Host
Rabbit
Reactivity
Human
Immunogen
This ACSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-556 amino acids from the C-terminal region of human ACSL3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ACSL3
NCBI Official Name
Long-chain-fatty-acid--CoA ligase 3
NCBI Organism
Homo sapiens
Background Reference 01
Weedon-Fekjaer, M.S., et al. J. Lipid Res. 51 (7) :1886-1896 (2010)
Background Reference 02
Cao, A., et al. J. Biol. Chem. 285 (22) :16664-16674 (2010)
Background Reference 03
Perera, F., et al. PLoS ONE (2), E4488 (2009) :
Background Reference 04
Yao, H., et al. J. Biol. Chem. 283 (2) :849-854 (2008)
Other Product Names
Long-chain-fatty-acid--CoA ligase 3, Long-chain acyl-CoA synthetase 3, LACS 3, ACSL3, ACS3, FACL3, LACS3
Tested Applications
WB
Physical Properties
Liquid

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