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ACSL4 Antibody

CAT: 0223-57-712Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-712Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
NCBI Gene ID
2182
Swiss Prot
O60488
Accession Number
O60488
Host
Rabbit
Reactivity
Human
Immunogen
This ACSL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ACSL4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ACSL4
NCBI Official Name
Long-chain-fatty-acid--CoA ligase 4
NCBI Organism
Homo sapiens
Background Reference 01
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
Background Reference 02
Zhang, Y., et al. Hum. Mol. Genet. 18 (20) :3894-3905 (2009)
Background Reference 03
Zeman, M., et al. Tohoku J. Exp. Med. 217 (4) :287-293 (2009)
Background Reference 04
An, C., et al. Neurosci. Lett. 441 (2) :197-200 (2008)
Other Product Names
Long-chain-fatty-acid--CoA ligase 4, Long-chain acyl-CoA synthetase 4, LACS 4, ACSL4, ACS4, FACL4, LACS4
Tested Applications
WB
Physical Properties
Liquid

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