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PHF21A Antibody

CAT: 0223-58-531Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-531Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535) /histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]) .
NCBI Gene ID
51317
Swiss Prot
Q96BD5
Accession Number
Q96BD5
Host
Rabbit
Reactivity
Human
Immunogen
This PHF21A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 436-464 amino acids from the Central region of human PHF21A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PHF21A
NCBI Official Name
PHD finger protein 21A
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Klajn, A., et al. J. Neurosci. 29 (19) :6296-6307 (2009)
Background Reference 03
Hailesellasse Sene, K., et al. BMC Genomics 8, 85 (2007) :
Background Reference 04
Shi, Y.J., et al. Mol. Cell 19 (6) :857-864 (2005)
Other Product Names
PHD finger protein 21A, BHC80a, BRAF35-HDAC complex protein BHC80, PHF21A, BHC80, KIAA1696
Tested Applications
WB
Protein ID
74731224
Physical Properties
Liquid

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