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ADAM23 Antibody

CAT: 0223-58-528Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-528Size:400 µL
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Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain.
NCBI Gene ID
8745
Swiss Prot
O75077
Accession Number
O75077
Host
Rabbit
Reactivity
Human
Immunogen
This ADAM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 803-831 amino acids from the C-terminal region of human ADAM23.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
92 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ADAM23
NCBI Official Name
Disintegrin and metalloproteinase domain-containing protein 23
NCBI Organism
Homo sapiens
Background Reference 01
Pan, Q., et al. Biochem. Biophys. Res. Commun. 401 (2) :306-312 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Ferreira, M.A., et al. Allergy 64 (11) :1623-1628 (2009)
Background Reference 04
Costa, M.D., et al. Neurosci. Lett. 461 (1) :16-20 (2009)
Other Product Names
Disintegrin and metalloproteinase domain-containing protein 23, ADAM 23, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3, MDC-3, ADAM23, MDC3
Tested Applications
WB
Physical Properties
Liquid

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