SIX3 Antibody

• Background:

  This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.

• NCBI Gene ID:

  6496

• Swiss Prot:

  O95343

• Accession Number:

  O95343

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SIX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the Central region of human SIX3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Chicken

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SIX3

• NCBI Official Name:

  Homeobox protein SIX3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Paulussen, A.D., et al. Eur. J. Hum. Genet. 18 (9) :999-1005 (2010)

• Background Reference 02:

  Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

• Background Reference 03:

  Hehr, U., et al. Hum. Genet. 127 (5) :555-561 (2010)

• Background Reference 04:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Other Product Names:

  Homeobox protein SIX3, Sine oculis homeobox homolog 3, SIX3

• Tested Applications:

  WB

• Physical Properties:

  Liquid