SIX5 Antibody

• Background:

  The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2.

• NCBI Gene ID:

  147912

• Swiss Prot:

  Q8N196

• Accession Number:

  Q8N196

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SIX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the Central region of human SIX5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  75 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SIX5

• NCBI Official Name:

  Homeobox protein SIX5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)

• Background Reference 02:

  Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)

• Background Reference 03:

  Hoskins, B.E., et al. Am. J. Hum. Genet. 80 (4) :800-804 (2007)

• Background Reference 04:

  Sato, S., et al. Hum. Mol. Genet. 11 (9) :1045-1058 (2002)

• Other Product Names:

  Homeobox protein SIX5, DM locus-associated homeodomain protein, Sine oculis homeobox homolog 5, SIX5, DMAHP

• Tested Applications:

  WB, IHC-P, IF

• Protein ID:

  150421671

• Physical Properties:

  Liquid