E2F7 Antibody

• Background:

  Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity) . Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.

• NCBI Gene ID:

  144455

• Swiss Prot:

  Q96AV8

• Accession Number:

  Q96AV8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This E2F7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-619 amino acids from the Central region of human E2F7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  100 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  E2F7

• NCBI Official Name:

  Transcription factor E2F7

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Transcription factor E2F7, E2F-7, E2F7

• Tested Applications:

  WB

• Protein ID:

  311033456

• Physical Properties:

  Liquid