Mouse Cdk20 Antibody

• Background:

  Cdk20 is involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity) . Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.

• NCBI Gene ID:

  105278

• Swiss Prot:

  Q9JHU3

• Accession Number:

  Q9JHU3

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Cdk20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-212 amino acids from the Central region of mouse Cdk20.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Cdk20

• NCBI Official Name:

  Cyclin-dependent kinase 20

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Qiu, H., et al. J. Biol. Chem. 283 (32) :22157-22165 (2008)

• Background Reference 02:

  Wohlbold, L., et al. Cell Cycle 5 (5) :546-554 (2006)

• Other Product Names:

  Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, CDK-related protein kinase PNQLARE, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, Cdk20, Ccrk, Cdch

• Tested Applications:

  WB

• Physical Properties:

  Liquid