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SPINT1 Antibody

CAT: 0223-58-209Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-209Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
NCBI Gene ID
6692
Swiss Prot
O43278
Accession Number
O43278
Host
Rabbit
Reactivity
Human
Immunogen
This SPINT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human SPINT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SPINT1
NCBI Official Name
Kunitz-type protease inhibitor 1
NCBI Organism
Homo sapiens
Background Reference 01
Chen, Y.W., et al. J. Biol. Chem. 285 (41) :31755-31762 (2010)
Background Reference 02
Kauppinen, J.M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (9) :2133-2142 (2010)
Background Reference 03
Nakamura, K., et al. Int. J. Oncol. 35 (2) :239-248 (2009)
Background Reference 04
Wang, J.K., et al. Am. J. Physiol., Cell Physiol. 297 (2), C459-C470 (2009) :
Other Product Names
Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1, HAI-1, SPINT1, HAI1
Tested Applications
WB
Physical Properties
Liquid

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