Products for Research Use Only
RegisterLogin

RAD51C Antibody

CAT: 0223-58-132Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-58-132Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.
NCBI Gene ID
5889
Swiss Prot
O43502
Accession Number
O43502
Host
Rabbit
Reactivity
Human
Immunogen
This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RAD51C
NCBI Official Name
DNA repair protein RAD51 homolog 3
NCBI Organism
Homo sapiens
Background Reference 01
Zheng, Y., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 02
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Background Reference 03
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 04
Meindl, A., et al. Nat. Genet. 42 (5) :410-414 (2010)
Other Product Names
DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2
Tested Applications
WB
Physical Properties
Liquid

Related Products

CatalogName
45-132PRAD51C Peptide
23-011Rad51D Antibody
22-589RAD51B Antibody
19-263Rad51D Antibody
22-093RAD51 Antibody
51-621RAD51 Antibody [13E4]
25-356RAD54B Antibody
25-355RAD54B Antibody
61-179RAD54B Antibody
16-491RAD54B Antibody

Alternative Products

CatalogName
DF4644-01Rad51C Antibody

Popular Products