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PEX3 (CT) Antibody

CAT: 0223-9665-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-9665-01Size:0.02 mg
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Background
PEX3 Antibody: PEX3 is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, PEX3 is necessary for the import of peroxisomal membrane proteins in the peroxisomes. Thus within the cell, PEX3 is stabilized by PEX19 preventing PEX3 aggregation. Mutations in the PEX19-binding domain of PEX3 reduce the affinity for PEX19 and destabilize PEX3.
NCBI Gene ID
8504
Swiss Prot
P56589
Accession Number
P56589
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
9665
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
PEX3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1203 – A549 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: monkey (100%), cow (100%)
Buffer
PEX3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
PEX3 antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Applications Notes
WB: 2 μ g/mL; IF: 20 μ g/mL. Antibody validated: Western Blot in human, mouse and rat samples; Immunofluorescence in human, mouse and rat samples. All other applications and species not yet tested.
Isoform
Human PEX3 has 1 isoform, including isoform 1 (373aa, 42kD) . Mouse PEX3 has 1 isoform (372aa, 42kD) . Rat PEX3 has one isoform (372aa, 42kD) . 9665 can detect PEX3 in human, mouse and rat.
Symbol
PEX3
Positive Control 2
Cat. No. 17-003 – A549 Cell Slide
NCBI Organism
Homo sapiens
Background Reference 01
Ghaedi et al. Mol Biol Cell. 2000; 11 (6) :2085-2102
Background Reference 02
Fang et al. J Cell Biol. 2004;164 (6) :863-875
Background Reference 03
Hattula et al. PloS One. 2014; 9 (7) :e103101
Background Reference 04
Schmidt et al. Traffic. 2012; 13 (9) :1244-1260
Other Product Names
PEX3 Antibody: Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3
Tested Applications
ELISA, WB, IF
Protein ID
3914303
Physical Properties
Liquid

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