ALDH8A1 Antibody

• Background:

  ALDH8A1 belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal.

• NCBI Gene ID:

  64577

• Swiss Prot:

  Q9H2A2

• Accession Number:

  Q9H2A2

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This ALDH8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-416 amino acids from the C-terminal region of human ALDH8A1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  53 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:2000

• Symbol:

  ALDH8A1

• NCBI Official Name:

  Aldehyde dehydrogenase family 8 member A1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lin, M., J. Biol. Chem. 275 (51), 40106-40112 (2000)

• Other Product Names:

  Aldehyde dehydrogenase family 8 member A1, 121-, Aldehyde dehydrogenase 12, ALDH8A1, ALDH12

• Tested Applications:

  WB

• Protein ID:

  74752601

• Physical Properties:

  Liquid