Products for Research Use Only

CD70 Antibody

CAT: 0223-57-954Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-954Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
NCBI Gene ID
970
Swiss Prot
P32970
Accession Number
P32970
Host
Rabbit
Reactivity
Human
Immunogen
This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Symbol
CD70
NCBI Official Name
CD70 antigen
NCBI Organism
Homo sapiens
Background Reference 01
Arimoto-Miyamoto, K., et al. Immunology 130 (1) :137-149 (2010)
Background Reference 02
Shaw, J., et al. Blood 115 (15) :3051-3057 (2010)
Background Reference 03
Yu, S.E., et al. Mol. Cells 29 (2) :217-221 (2010)
Background Reference 04
Kozlowska, A., et al. J. Rheumatol. 37 (1) :53-59 (2010)
Other Product Names
CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7
Tested Applications
WB, IHC-P
Protein ID
21431837
Physical Properties
Liquid