Mouse Dapk3 Antibody

CAT: 0223-57-930Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-930Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection (By similarity) .
NCBI Gene ID
13144
Swiss Prot
O54784
Accession Number
O54784
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Dapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from the Central region of mouse Dapk3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
Dapk3
NCBI Official Name
Death-associated protein kinase 3
NCBI Organism
Mus musculus
Background Reference 01
Chang, A.N., et al. J. Biol. Chem. 285 (8) :5122-5126 (2010)
Background Reference 02
Ohbayashi, N., et al. Biochem. Biophys. Res. Commun. 372 (4) :708-712 (2008)
Background Reference 03
Wooldridge, A.A., et al. J. Biol. Chem. 283 (17) :11850-11859 (2008)
Background Reference 04
Shoval, Y., et al. PLoS Genet. 3 (10) :1884-1893 (2007)
Other Product Names
Death-associated protein kinase 3, DAP kinase 3, DAP-like kinase, Dlk, MYPT1 kinase, ZIP-kinase, Dapk3, Zipk
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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