Mouse Prkcd Antibody

• Background :

  This is calcium-independent, phospholipid-dependent, serine-and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin (By similarity) .

• NCBI Gene ID :

  18753

• Swiss Prot :

  P28867

• Accession Number :

  P28867

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This Mouse Prkcd antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of mouse Prkcd.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  78 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  Prkcd

• NCBI Official Name :

  Protein kinase C delta type

• NCBI Organism :

  Mus musculus

• Background Reference 01 :

  Ronda, A.C., et al. J. Steroid Biochem. Mol. Biol. 122 (4) :287-294 (2010)

• Background Reference 02 :

  Li, X., et al. J. Am. Soc. Nephrol. 21 (7) :1115-1124 (2010)

• Background Reference 03 :

  Romanova, L.Y., et al. J. Cell. Sci. 123 (PT 9), 1567-1577 (2010) :

• Background Reference 04 :

  White, M.C., et al. PLoS Genet. (6), E1000984 (2010) :

• Other Product Names :

  Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, Protein kinase C delta type regulatory subunit, Protein kinase C delta type catalytic subunit, Sphingosine-dependent protein kinase-1, SDK1, Prkcd, Pkcd

• Tested Applications :

  WB

• Physical Properties :

  Liquid