Mouse Prkcd Antibody

• Background:

  This is calcium-independent, phospholipid-dependent, serine-and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin (By similarity) .

• NCBI Gene ID:

  18753

• Swiss Prot:

  P28867

• Accession Number:

  P28867

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Prkcd antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of mouse Prkcd.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  78 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Prkcd

• NCBI Official Name:

  Protein kinase C delta type

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Ronda, A.C., et al. J. Steroid Biochem. Mol. Biol. 122 (4) :287-294 (2010)

• Background Reference 02:

  Li, X., et al. J. Am. Soc. Nephrol. 21 (7) :1115-1124 (2010)

• Background Reference 03:

  Romanova, L.Y., et al. J. Cell. Sci. 123 (PT 9), 1567-1577 (2010) :

• Background Reference 04:

  White, M.C., et al. PLoS Genet. (6), E1000984 (2010) :

• Other Product Names:

  Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, Protein kinase C delta type regulatory subunit, Protein kinase C delta type catalytic subunit, Sphingosine-dependent protein kinase-1, SDK1, Prkcd, Pkcd

• Tested Applications:

  WB

• Physical Properties:

  Liquid