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PHLDA2 Antibody

CAT: 0223-57-773Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-773Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.
NCBI Gene ID
7262
Swiss Prot
Q53GA4
Accession Number
Q53GA4
Host
Rabbit
Reactivity
Human
Immunogen
This PHLDA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human PHLDA2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Symbol
PHLDA2
NCBI Official Name
Pleckstrin homology-like domain family A member 2
NCBI Organism
Homo sapiens
Background Reference 01
O'Seaghdha, C.M., et al. Hum. Mol. Genet. 19 (21) :4296-4303 (2010)
Background Reference 02
Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34 (5) :840-852 (2010)
Background Reference 03
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Background Reference 04
Tang, K.F., et al. Biochim. Biophys. Acta 1770 (5) :820-825 (2007)
Other Product Names
Pleckstrin homology-like domain family A member 2, Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein, Imprinted in placenta and liver protein, Tumor-suppressing STF cDNA 3 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein, p17-Beckwith-Wiedemann region 1 C, p17-BWR1C, PHLDA2, BWR1C, HLDA2, IPL, TSSC3
Tested Applications
WB, IHC-P
Protein ID
84029394
Physical Properties
Liquid

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