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HRH1 Antibody

CAT: 0223-57-725Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-725Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].
NCBI Gene ID
3269
Swiss Prot
P35367
Accession Number
P35367
Host
Rabbit
Reactivity
Human
Immunogen
This HRH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the Central region of human HRH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
HRH1
NCBI Official Name
Histamine H1 receptor
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Background Reference 03
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 04
Notcovich, C., et al. Exp. Cell Res. 316 (3) :401-411 (2010)
Other Product Names
Histamine H1 receptor, H1R, HH1R, HRH1
Tested Applications
WB, IHC-P
Protein ID
547645
Physical Properties
Liquid

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