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GTF2A1L Antibody

CAT: 0223-57-690Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-690Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
NCBI Gene ID
11036
Swiss Prot
Q9UNN4
Accession Number
Q9UNN4
Host
Rabbit
Reactivity
Human
Immunogen
This GTF2A1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human GTF2A1L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GTF2A1L
NCBI Official Name
TFIIA-alpha and beta-like factor
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Kim, M., et al. J. Biol. Chem. 281 (45) :34288-34298 (2006)
Background Reference 03
Howe, M.L., et al. Stem Cells Dev. 15 (2) :175-190 (2006)
Background Reference 04
Huang, M., et al. Int. J. Mol. Med. 17 (4) :599-604 (2006)
Other Product Names
TFIIA-alpha and beta-like factor, General transcription factor II A, 1-like factor, GTF2A1L, ALF, GTF2A1LF
Tested Applications
WB
Protein ID
327478545
Physical Properties
Liquid

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