RPL8 Antibody

• Background:

  Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].

• NCBI Gene ID:

  6132

• Swiss Prot:

  P62917

• Accession Number:

  P62917

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RPL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the C-terminal region of human RPL8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Zebrafish, Mouse, Rat, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RPL8

• NCBI Official Name:

  60S ribosomal protein L8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Salas, S., et al. Int. J. Cancer 125 (4) :851-860 (2009)

• Background Reference 02:

  Stelzl, U., et al. Cell 122 (6) :957-968 (2005)

• Background Reference 03:

  Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)

• Background Reference 04:

  Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)

• Other Product Names:

  60S ribosomal protein L8, RPL8

• Tested Applications:

  WB

• Protein ID:

  51702823

• Physical Properties:

  Liquid