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RPL3 Antibody

CAT: 0223-57-031Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-031Size:400 µL
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Background
Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].
NCBI Gene ID
6122
Swiss Prot
P39023
Accession Number
P39023
Host
Rabbit
Reactivity
Human
Immunogen
This RPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the Central region of human RPL3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rat, Yeast
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Symbol
RPL3
NCBI Official Name
60S ribosomal protein L3
NCBI Organism
Homo sapiens
Background Reference 01
Russo, A., et al. Biochim. Biophys. Acta 1799 (5-6), 419-428 (2010) :
Background Reference 02
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Background Reference 03
Tu, L.C., et al. Mol. Cell Proteomics 6 (4) :575-588 (2007)
Background Reference 04
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Other Product Names
60S ribosomal protein L3, HIV-1 TAR RNA-binding protein B, TARBP-B, RPL3
Tested Applications
WB, IHC-P
Protein ID
730565
Physical Properties
Liquid

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