WNT3 Antibody

CAT: 0223-57-501Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-501Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
NCBI Gene ID
7473
Swiss Prot
P56703
Accession Number
P56703
Host
Rabbit
Reactivity
Human
Immunogen
This WNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-184 amino acids from the Central region of human WNT3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WNT3
NCBI Official Name
Proto-oncogene Wnt-3
NCBI Organism
Homo sapiens
Background Reference 01
Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)
Background Reference 02
Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)
Background Reference 03
Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)
Background Reference 04
Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)
Other Product Names
Proto-oncogene Wnt-3, Proto-oncogene Int-4 homolog, WNT3, INT4
Tested Applications
WB
Protein ID
14424477
Physical Properties
Liquid

Related Products

CatalogName
46-598PWNT3 Peptide
19-905WNT2 Antibody
18-659WNT1 Antibody
58-564WNT6 Antibody
8063-01mgWNT5 Antibody
8063-002mgWNT5 Antibody
15-071WNT2 Antibody
8063-01WNT5 Antibody
23-198WNT4 Antibody
13-232WNT3A Antibody

Alternative Products

CatalogName
F43549-0.4MLWNT3 Antibody
MBS178037-01Anti-Wnt3 Antibody
MBS8001541-01WNT3 Antibody: RPE
MBS8001538-01WNT3 Antibody: HRP
48348-01WNT3A/WNT3 Antibody
31702-01WNT3 Polyclonal Antibody
MBS8001537-01WNT3 Antibody: FITC
MBS8001536-01WNT3 Antibody: Biotin
581607-01Wnt3

Popular Products