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WNT6 Antibody

CAT: 0223-58-564Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-564Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
NCBI Gene ID
7475
Swiss Prot
Q9Y6F9
Accession Number
Q9Y6F9
Host
Rabbit
Reactivity
Human
Immunogen
This WNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human WNT6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WNT6
NCBI Official Name
Protein Wnt-6
NCBI Organism
Homo sapiens
Background Reference 01
Wang, C., et al.Endod 36 (2) :238-243 (2010)
Background Reference 02
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 03
Adaimy, L., et al. Am. J. Hum. Genet. 81 (4) :821-828 (2007)
Background Reference 04
Beaty, T.H., et al. Hum. Genet. 120 (4) :501-518 (2006)
Other Product Names
Protein Wnt-6, WNT6
Tested Applications
WB
Protein ID
14424016
Physical Properties
Liquid

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