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CHRNA5 Antibody

CAT: 0223-57-414Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-414Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2) .
NCBI Gene ID
1138
Swiss Prot
P30532
Accession Number
P30532
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CHRNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human CHRNA5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CHRNA5
NCBI Official Name
Neuronal acetylcholine receptor subunit alpha-5
NCBI Organism
Homo sapiens
Background Reference 01
Wessel, J., et al. Neuropsychopharmacology 35 (12) :2392-2402 (2010)
Background Reference 02
Erlich, P.M., et al. Hum. Genet. 128 (5) :491-499 (2010)
Background Reference 03
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 04
Falvella, F.S., et al. J. Natl. Cancer Inst. 102 (17) :1366-1370 (2010)
Other Product Names
Neuronal acetylcholine receptor subunit alpha-5, CHRNA5, NACHRA5
Tested Applications
WB
Protein ID
2506126
Physical Properties
Liquid

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