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SYT1 Antibody

CAT: 0223-57-214Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-214Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]) .
NCBI Gene ID
6857
Swiss Prot
P21579
Accession Number
P21579
Host
Rabbit
Reactivity
Human
Immunogen
This SYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the C-terminal region of human SYT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
SYT1
NCBI Official Name
Synaptotagmin-1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (2), G203-G211 (2010) :
Background Reference 03
Kathir, K.M., et al. Biochim. Biophys. Acta 1798 (2) :297-302 (2010)
Background Reference 04
Pattaro, C., et al. BMC Med. Genet. 11, 41 (2010) :
Other Product Names
Synaptotagmin-1, Synaptotagmin I, SytI, p65, SYT1, SVP65, SYT
Tested Applications
WB, IHC-P
Protein ID
135086
Physical Properties
Liquid

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