ACTG2 Antibody

• Background:

  Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.

• NCBI Gene ID:

  72

• Swiss Prot:

  P63267

• Accession Number:

  P63267

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ACTG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human ACTG2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ACTG2

• NCBI Official Name:

  Actin, gamma-enteric smooth muscle

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sun, Q., et al. J. Biol. Chem. 284 (47) :32582-32590 (2009)

• Background Reference 02:

  Laasanen, J., et al. Fetal. Diagn. Ther. 23 (1) :36-40 (2008)

• Background Reference 03:

  Goldberg, M.T., et al. J. Invest. Dermatol. 127 (11) :2645-2655 (2007)

• Background Reference 04:

  Yonemoto, S., et al. Clin. Exp. Nephrol. 10 (3) :186-192 (2006)

• Other Product Names:

  Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin, ACTG2, ACTA3, ACTL3, ACTSG

• Tested Applications:

  WB, IHC-P

• Protein ID:

  54036679

• Physical Properties:

  Liquid