CTGF Antibody

• Background:

  The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq].

• NCBI Gene ID:

  1490

• Swiss Prot:

  P29279

• Accession Number:

  P29279

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CTGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the Central region of human CTGF.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CTGF

• NCBI Official Name:

  Connective tissue growth factor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Behrens, M.E., et al. Oncogene 29 (42) :5667-5677 (2010)

• Background Reference 02:

  Cunningham, J.L., et al. Eur. J. Endocrinol. 163 (4) :691-697 (2010)

• Background Reference 03:

  Ito, Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F545-F558 (2010) :

• Background Reference 04:

  Adler, S.G., et al. ClinAm Soc Nephrol 5 (8) :1420-1428 (2010)

• Other Product Names:

  Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8, CTGF, CCN2, HCS24, IGFBP8

• Tested Applications:

  WB, IHC-P

• Protein ID:

  116241320

• Physical Properties:

  Liquid