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PRRG1 Antibody

CAT: 0223-57-002Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-002Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla) -containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
NCBI Gene ID
5638
Swiss Prot
O14668
Accession Number
O14668
Host
Rabbit
Reactivity
Human
Immunogen
This PRRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human PRRG1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PRRG1
NCBI Official Name
Transmembrane gamma-carboxyglutamic acid protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 02
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)
Background Reference 03
Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)
Background Reference 04
Kulman, J.D., et al. Proc. Natl. Acad. Sci. U.S.A. 94 (17) :9058-9062 (1997)
Other Product Names
Transmembrane gamma-carboxyglutamic acid protein 1, Proline-rich gamma-carboxyglutamic acid protein 1, Proline-rich Gla protein 1, PRRG1, PRGP1, TMG1
Tested Applications
WB
Physical Properties
Liquid

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