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TRIM37 Antibody

CAT: 0223-56-970Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-970Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq].
NCBI Gene ID
4591
Swiss Prot
O94972
Accession Number
O94972
Host
Rabbit
Reactivity
Human
Immunogen
This TRIM37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 936-964 amino acids from the C-terminal region of human TRIM37.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TRIM37
NCBI Official Name
E3 ubiquitin-protein ligase TRIM37
NCBI Organism
Homo sapiens
Background Reference 01
Xin, X., et al. Genome Res. 19 (7) :1262-1269 (2009)
Background Reference 02
Karlberg, S., et al. Mod. Pathol. 22 (4) :570-578 (2009)
Background Reference 03
Doganc, T., et al. Clin. Dysmorphol. 16 (3) :173-176 (2007)
Background Reference 04
Hamalainen, R.H., et al. Clin. Genet. 70 (6) :473-479 (2006)
Other Product Names
E3 ubiquitin-protein ligase TRIM37, 632-, Mulibrey nanism protein, Tripartite motif-containing protein 37, TRIM37, KIAA0898, MUL, POB1
Tested Applications
WB
Physical Properties
Liquid

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