RNF43 Antibody

• Background :

  RNF43 is a HAP95 (AKAP8L; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]; Sugiura et al., 2008 [PubMed 18313049]) .

• NCBI Gene ID :

  54894

• Swiss Prot :

  Q68DV7

• Accession Number :

  Q68DV7

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This RNF43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 amino acids from the C-terminal region of human RNF43.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  86 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  RNF43

• NCBI Official Name :

  E3 ubiquitin-protein ligase RNF43

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Low, S.K., et al. PLoS ONE (7), E11824 (2010) :

• Background Reference 02 :

  Sugiura, T., et al. Exp. Cell Res. 314 (7) :1519-1528 (2008)

• Background Reference 03 :

  Uchida, N., et al. Clin. Cancer Res. 10 (24) :8577-8586 (2004)

• Background Reference 04 :

  Yagyu, R., et al. Int. J. Oncol. 25 (5) :1343-1348 (2004)

• Other Product Names :

  E3 ubiquitin-protein ligase RNF43, 632-, RING finger protein 43, RNF43

• Tested Applications :

  WB, IHC-P

• Protein ID :

  74757361

• Physical Properties :

  Liquid