NAT1 Antibody

• Background:

  This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  9

• Swiss Prot:

  P18440

• Accession Number:

  P18440

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human NAT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rb

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  34 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NAT1

• NCBI Official Name:

  Arylamine N-acetyltransferase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

• Background Reference 03:

  Minchin, R.F., et al. Int. J. Biochem. Cell Biol. 39 (11) :1999-2005 (2007)

• Background Reference 04:

  Barker, D.F., et al. Pharmacogenet. Genomics 16 (7) :515-525 (2006)

• Other Product Names:

  Arylamine N-acetyltransferase 1, Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase, MNAT, N-acetyltransferase type 1, NAT-1, NAT1, AAC1

• Tested Applications:

  WB

• Protein ID:

  114234

• Physical Properties:

  Liquid