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NAT1 Antibody

CAT: 0223-56-897Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-897Size:400 µL
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Background
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
9
Swiss Prot
P18440
Accession Number
P18440
Host
Rabbit
Reactivity
Human
Immunogen
This NAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human NAT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NAT1
NCBI Official Name
Arylamine N-acetyltransferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 03
Minchin, R.F., et al. Int. J. Biochem. Cell Biol. 39 (11) :1999-2005 (2007)
Background Reference 04
Barker, D.F., et al. Pharmacogenet. Genomics 16 (7) :515-525 (2006)
Other Product Names
Arylamine N-acetyltransferase 1, Arylamide acetylase 1, Monomorphic arylamine N-acetyltransferase, MNAT, N-acetyltransferase type 1, NAT-1, NAT1, AAC1
Tested Applications
WB
Protein ID
114234
Physical Properties
Liquid

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