LIMD1 Antibody

• Background:

  LIMD1 is a transcriptional regulator that inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. May act as a tumor suppressor by inhibiting cell proliferation.

• NCBI Gene ID:

  8994

• Swiss Prot:

  Q9UGP4

• Accession Number:

  Q9UGP4

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This LIMD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the C-terminal region of human LIMD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  72 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  LIMD1

• NCBI Official Name:

  LIM domain-containing protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ghosh, S., et al. Mol. Cancer 9, 58 (2010) :

• Background Reference 02:

  Sharp, T.V., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (50) :19932-19937 (2008)

• Background Reference 03:

  Spendlove, I., et al. Int. J. Cancer 123 (10) :2247-2253 (2008)

• Background Reference 04:

  Huggins, C.J., et al. Cancer Lett. 267 (1) :55-66 (2008)

• Other Product Names:

  LIM domain-containing protein 1, LIMD1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  47605932

• Physical Properties:

  Liquid