GNLY Antibody

• Background:

  The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID:

  10578

• Swiss Prot:

  P22749

• Accession Number:

  P22749

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  16 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GNLY

• NCBI Official Name:

  Granulysin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Xing, J., et al. J. Immunol. 185 (9) :5074-5081 (2010)

• Background Reference 02:

  Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)

• Background Reference 03:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 04:

  Yang, C., et al. Int. J. Tuberc. Lung Dis. 13 (11) :1360-1366 (2009)

• Other Product Names:

  Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519

• Tested Applications:

  WB

• Protein ID:

  116242500

• Physical Properties:

  Liquid