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GNLY Antibody

CAT: 0223-56-835Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-835Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
10578
Swiss Prot
P22749
Accession Number
P22749
Host
Rabbit
Reactivity
Human
Immunogen
This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
16 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GNLY
NCBI Official Name
Granulysin
NCBI Organism
Homo sapiens
Background Reference 01
Xing, J., et al. J. Immunol. 185 (9) :5074-5081 (2010)
Background Reference 02
Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)
Background Reference 03
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 04
Yang, C., et al. Int. J. Tuberc. Lung Dis. 13 (11) :1360-1366 (2009)
Other Product Names
Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519
Tested Applications
WB
Protein ID
116242500
Physical Properties
Liquid

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