GNLY Antibody

• Background :

  The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID :

  10578

• Swiss Prot :

  P22749

• Accession Number :

  P22749

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  16 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  GNLY

• NCBI Official Name :

  Granulysin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Xing, J., et al. J. Immunol. 185 (9) :5074-5081 (2010)

• Background Reference 02 :

  Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)

• Background Reference 03 :

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 04 :

  Yang, C., et al. Int. J. Tuberc. Lung Dis. 13 (11) :1360-1366 (2009)

• Other Product Names :

  Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519

• Tested Applications :

  WB

• Protein ID :

  116242500

• Physical Properties :

  Liquid