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DDX3Y Antibody

CAT: 0223-56-646Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-646Size:400 µL
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Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.
NCBI Gene ID
8653
Swiss Prot
O15523
Accession Number
O15523
Host
Rabbit
Reactivity
Human
Immunogen
This DDX3Y antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of human DDX3Y.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DDX3Y
NCBI Official Name
ATP-dependent RNA helicase DDX3Y
NCBI Organism
Homo sapiens
Background Reference 01
Rosinski, K.V., et al. Blood 111 (9) :4817-4826 (2008)
Background Reference 02
Lardone, M.C., et al. Mol. Hum. Reprod. 13 (10) :705-712 (2007)
Background Reference 03
Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005) :
Background Reference 04
Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)
Other Product Names
ATP-dependent RNA helicase DDX3Y, DEAD box protein 3, Y-chromosomal, DDX3Y, DBY
Tested Applications
WB
Physical Properties
Liquid

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