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RPL15 Antibody

CAT: 0223-56-636Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-636Size:400 µL
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Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Although this gene has been referred to as RPL10, its official symbol is RPL15. This gene has been shown to be overexpressed in some esophageal tumors compared to normal matched tissues. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
NCBI Gene ID
6138
Swiss Prot
P61313
Accession Number
P61313
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This RPL15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human RPL15.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Symbol
RPL15
NCBI Official Name
60S ribosomal protein L15
NCBI Organism
Homo sapiens
Background Reference 01
Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :
Background Reference 02
Wang, H., et al. BMC Cancer 6, 91 (2006) :
Background Reference 03
Andersen, J.S., et al. Nature 433 (7021) :77-83 (2005)
Background Reference 04
Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :
Other Product Names
60S ribosomal protein L15, RPL15, EC45
Tested Applications
WB, IHC-P, Flow
Protein ID
47117726
Physical Properties
Liquid

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